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Are Lactate Levels Predictive of In-Hospital Mortality?

Noviembre 21, 2018 - Noticia en Lactato en Clínica

This article, written by Kruse et al. under the title "Blood lactate as a predictor for in-hospital mortality in patients admitted acutely to hospital: a systematic review", aims to examine whether lactate levels are predictive of in-hospital mortality in critically ill patients.

 

The aim of this review was to evaluate the scientific literature to uncover whether elevated blood lactate levels are predictive for in-hospital mortality in patients in the acute setting. 

 

To do so, the authors identified studies by a systematic search using PubMed, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, and CINAHL up to April 2011.

 

The initial search identified 1.677 abstracts, which were evaluated for relevance. 66 articles were considered potentially relevant and evaluated in full text. Ultimately 33 articles were selected.

 

The authors concluded that blood lactate monitoring is useful for risk assessment in patients admitted acutely to hospital, and especially the trend in serial lactate monitoring is valuable in predicting in-hospital mortality. All patients with a lactate at admission above 2.5 mM should be closely monitored for signs of deterioration, and patients with even lower lactate levels should be considered for serial lactate monitoring.

 

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Tags: lactate, blood lactate, in-hospital mortality, lactate levels